Chinese Journal of Pharmacology and Toxicology 2013 Issue 4 Prediction of human pharmacokinetics and its application in drug discovery and development

Prediction of human pharmacokinetics and its application in drug discovery and development
LI Hua;,ZHUANG Xiao-mei;

..............page:611-615

Changes of neurite outgrowth inhibitor-A and calcitonin gene-related peptide mRNA expression in periaqueductal gray of hindpaw inflammatory rats induced by formaldehyde
CHENG Min;,FANG Chun-yan;,LI Ning;,MA Juan;,MENG Di;,WANG Yan;,ZHANG Guang-xue;

..............page:616-621

Norcantharidin downregulates programmed cell death 4 expression in human gastric cancer cells
CAO Chun-ming;,LI Zi-mu;,SUN Zhen-xiao;,WANG Han-qing;,WU Yang;

..............page:622-628

Protection of sarsasapogenin against amyloid beta-protein induced neurotoxicity in primary cultured hippocampal neurons of neonatal rats
JIN Ying;,JIN Ying-xin;,LI Hong-xiu;,QU Wen-hui;,SUI Hai-juan;,WANG Li-jun;,YU Sheng-xue;

..............page:629-634

Sarsasapogenin inhibits amyloid beta-protein induced decrease of synaptophysin in hippocampal neurons of neonatal rats via up-regulating PI3K/Akt/GSK3 pathway
jin ying ;, jin ying xin ;, li hong xiu ;, liu zhuo ;, lu ying ;, qu wen hui ;, sui hai juan ;, yu sheng xue ;

..............page:635-640

Inhibitory effect of total ginsenosides on cardiomyocyte hypertrophy induced by angiotensin Ⅱ in neonatal rats
DENG Jiang;,HUANG Xie-nan;,L(U) Xin-tong;,YANG Dan-li;

..............page:641-645

Anticoagulation effect of Protobothrops mucrosquamatus venom
LI Ya-nan;,SUN Qian-yun;

..............page:646-649

Effect of carbon tetrachloride on total bile acid, α-glutathione-S-transferase, purine nucleoside phosphorylase and ornithine carbamyl transferase in serum of rats during early liver injury
JIN Ruo-min;,QIAO Jing-yi;,YAO Guang-tao;,ZHOU Lu;

..............page:650-656

Antitumor activity of histone deacetylases inhibitor, DWP0016, in lung carcinoma A549 cells and xenograft mouse model
DENG Wei-ping;,JIN Hui;,LIU Jian-wen;,LIU Li-feng;

..............page:657-662

Effect of juglone alone or combined with cisplatin on survival and apoptosis of human cervical cancer HeLa cells
jiang yan xia ;, jin zuo ;, li zuo ;, luo jun ;, xu jun jie ;, zhang wei ;, zhao xing yu ;, zhu wen he ;

..............page:663-667

Effect of paeoniflorin on hypothalamic-pituitary-adrenal axis of rats with collagen-induced arthritis
TANG Xiang-lin;,YI Jian-feng;

..............page:668-672

xin xi dong tai

..............page:672,690,726,后插1-后插2

Screening and chemical component analysis of anti-hyperuricemic active fraction of ethanol extract from Polyrhachis vicina Roger in hyperuricemia model mice
he fei ;, he kai jia ;, lu wen jie ;, lv ji hua ;, su hua ;, su qi biao ;, wei gui ning ;, ya qi kang ;, zeng xian biao ;

..............page:673-677

Effect of compound Danshen Dripping Pills on rat hepatic cytochrome P450
chen zhi wu ;, hu dong hua ;, li zuo ;, liang qian de ;, ma zeng chun ;, tan hong ling ;, tang xiang lin ;, wang yu guang ;, xiao cheng rong ;

..............page:678-684

Neurotoxicity of haloperidol on zebrafish embryos
CAO Wen-zhi;,JIANG Guo-liang;,LI Pin;,LIU Yun;,SUI Jian-qiang;,WANG Zhen;

..............page:685-690

Promethazine aggravates arrhythmia induced by Qing-kai-ling injection
CHEN Long;,LI Xue-hua;,LIU Lei;,LUO Zhuo-ka;,SHENG Xiao-bo;,WANG Zhong-yue;

..............page:691-697

PM2.5 induces oxidative stress and autophagy in lung epithelial MLE-12 cells
CHEN De-liang;,DENG Xiao-bei;,DING Wen-jun;,LONG Fang;,ZHANG Fang;

..............page:698-703

Toxic effect of yuanhuacine on human L02 liver cells by metabolomics
chen yan zuo ;, duan jin zuo ;, fan xin sheng ;, guo jian ming ;, ma hong yue ;, qian ye fei ;, shang er zuo ;, shi jie zuo ;, tang yu ping ;

..............page:704-709

Lipotoxicity of free fatty acid and its oxidative stress mechanism in L02 cells
HONG Zhen-feng;,LIU Yan;,SHI Wen-rong;

..............page:710-714

Establishment of female rat model for post-traumatic stress disorder induced by single prolonged stress
fan qiong yin ;, ge han xiao ;, hu jing zuo ;, li yang ;, li yun feng ;, xue rui ;, zhang ting ting ;, zhang you zhi ;

..............page:715-719

Vilazodone: a new generation of antidepressants with multiple targets and new mechanisms
HONG Hao;,LI Yun-feng;,WANG Xiao-yun;

..............page:720-726

Progress relating to mitochondria dysfunction and Parkinson disease
LI Yu-juan;,WANG Dan-qiao;

..............page:727-730

Progress in acetylcholinesterase reactivators aiming to cross blood-brain barriers
LI Song;,WEI Zhao;,ZHENG Zhi-bing;

..............page:731-738

Recent advances of combretastatin A4-type vascular disrupting agents
HAN Fu-guo;,LI Jing;,QI Xin;

..............page:739-744

Advances in studies on chemical constituents and pharmacological effects of Paeonia lactiflora Pall.
CHEN Man-li;,JIN Ying-shan;,TAO Jun;

..............page:745-750

Advances in research on immune organs and immunocytes of nonhuman primates
cui zuo ;, huang zuo ;, huang zhi zuo ;, huo gui tao ;, lin zhi ;, lv jian jun ;, qu zhe ;, yang yan wei ;, zhang zuo ;

..............page:751-754

Progress in pharmacotherapy and mechanism of lipid homeostasis in liver cells
DU Rao;,XIE Mei-lin;

..............page:755-759

Qualitative and quantitative methods for liver cytochrome P450's reaction phenotyping in drug discovery and development
LIU Hai-yan;

..............page:760-765

Progress in mechanisms of kidney damage induced by cadmium,lead, mercury, arsenic and chromium
HU Jian-an;,SHEN Yun-shuai;

..............page:766-768