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Chinese Journal of New Drugs
1003-3734
2016 Issue 19
A novel prostacyclin receptor agonist,selexipag
ZHANG Xin-fang;SUN Hui-juan;ZHU Mei-hua;WANG Li-li;LIU Zheng-ping;ZHANG Jian-qiang;Shandong Academy of Pharmaceutical Sciences;Shandong Provincal Key Laboratory of Biopharmaceuticals;Shandong Freda Pharmaceutical Group Co.;Ltd.;Shandong Provincial Key Laboratory of Mucosal and Transdermal Drug Delivery Technologies;
..............page:2161-2164
First orphan drug for hereditary factor X deficiency:coagadex
ZHAO Xiao-juan;ZHOU Li-ming;ZHAO Yong-hong;Department of Pharmacy;the Second Hospital of Hebei Medical University;New Drug Research and Development Co.;Ltd.;North China Pharmaceutical Group Corporation;
..............page:2165-2167
Research on the first generic drug system and the patent challenge strategy of USA
LIN Tao-xi;YU Na;HUANG Lu;Sunshine Lake Pharma Co.;Ltd.;Humanwell Healthcare Co.;Ltd.;
..............page:2168-2173
Global regulatory requirement and development strategy for pediatric drugs
HUANG Fang-hua;WANG Qing-li;Jim Ridings;Susan Watts;WANG Ying;ZHANG Yun;Center for Drug Evaluation;China Food and Drug Administration;Toxicology and Biometabolism;Glaxo Smith Kline;R&D Chief Regulatory Office;Glaxo Smith Kline;Safety Assessment;GSK Shanghai R&D;
..............page:2174-2182
Biological activity screening of DL0805 derivatives and the cytotoxicity evaluation
YUAN Tian-yi;WANG Su-bo;CHEN Yu-cai;ZHANG Hui-fang;JIAO Xiao-zhen;XIE Ping;FANG Lian-hua;DU Guan-hua;Beijing Key Laboratory of Drug Targets Identification and Drug Screening;Institute of Materia Medica;Chinese Academy of Medical Sciences and Peking Union Medical College;National Glycoengineering Research Center;Shandong University;Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation;Institute of Materia Medica;Chinese Academy of Medical Sciences and Peking Union Medical College;
..............page:2183-2188
Safety evaluation of repeated intramuscular injection of CpG 684-HBV vaccine in rats
LIU Li;WANG Chao;LIN Zhi;MENG Jian-hua;LI Ming;MIAO Yu-fa;YANG Yan-wei;ZHANG Yi;SHAO Yan;WANG Li-ying;YU Yong-li;WANG Ju-feng;LI Bo;National Center for Safety Evaluation of Drugs;National Institute for Food and Drug Control;Key Laboratory of Beijing for Nonclinical Safety Evaluation Research of Drugs;Yunnan Walvax Biotechnology Co.;Ltd.;Changchun Huapu Bio-Tech Co.;Ltd.;College of Basic Medical Sciences;Bethune Medical School;Jilin University;
..............page:2189-2198
The new direction in the development of antibiotics:anti-bacterial antibody drugs
WANG Zhi-ming;State Key Laboratory of Antibody Drug Development;NCPC New Drug Research and Development Co.;Ltd.;
..............page:2199-2204
The status and prospect of research and development of drug combinations
CHEN Guang-liang;ZHANG Lei;CHEN Ping;XU Xi-ping;Integrative Medicine College;Anhui University of Chinese Medicine;Shenzhen Ausa Pharmaceutical Co;Ltd;National Clinical Research Center for Kidney Disease;Southern Medical University;
..............page:2205-2210
Influencing factors of the protective RISK pathway of myocardial ischemia/reperfusion
GUAN Yue;WEI Guo;DUAN Jia-lin;YIN Ying;GUO Chao;ZHU Yan-rong;WANG Yan-hua;XI Miao-miao;WEN Ai-dong;Department of Pharmacy;Xijing Hospital;the Fourth Military Medical University;
..............page:2211-2217
Recent progress in research of pH-sensitive polymeric micelles as drug delivery system
WANG Di-shi;ZHOU Yan-xia;LI Cheng-wei;QU Xiao-you;WANG Zi-qi;Li Xin-ru;YI Chong-qin;LIU Yan;Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems;School of Pharmaceutical Sciences;Peking University;Founder Medical Research Institute Co.;Ltd.;
..............page:2218-2224
Preliminary observation of oxycodone hydrochloride injection for general anesthesia induction in patients undergoing thyroid surgery
YAO Yue-qin;FAN Zhi-yi;LIU Ying-hua;CHEN Ji-heng;Department of Anesthesiology;Peking University Cancer Hospital & Institute;Key Laboratory of Carcinogenesis and Translational Research;Ministry of Education;
..............page:2225-2228
Effects of dexmedetomidine combined with propofol on painless gastroscopy and colonoscopy in the elderly
SHI Cheng-mei;ZHOU Yong-de;ZHANG Li-ping;GUO Xiang-yang;GUO Yu-fei;Department of Anesthesiology;Peking University Third Hospital;Department of Anesthesiology;Tsinghua University Yuquan Hospital;
..............page:2229-2233
Bioequivalence test of domestic levetiracetam tablets in healthy volunteers
DENG Ming;MA Jing-yi;MENG Ling-jie;LI Yu-qiao;GUO Yu-xiao;YI Chong-qin;LIU Hui-chen;Department of Clinical Pharmacology;Aerospace Center Hospital;Pkucare Pharmaceutical R&D Center;
..............page:2234-2239
Review & approval process of generic drugs in US
LEI Ji-feng;YANG Jian-hong;Shanghai Anbison Lab.Co.;Ltd.;Drug Evaluation Center;CFDA;
..............page:2240-2249
Efficacy and mechanism of ulinastatin on acute lung injury induced by blast in rabbits
LI Cheng-en;LI Shu-wen;HAO Jian;MA Hong-hao;QIAN Jun;LI Lu-huan;HE Hui-bo;HUANG Xin;Department of Liberation Army Hangzhou Clinical College of Anhui Medical University;Department of Cardiopulmonary Rehabilitation;Hangzhou 128 Hospital;Department of Modern Mechanics;University of Science and Technology of China;
..............page:2250-2254
Optimization of water extraction and purification process of Lumbricus by multiple indicators grading method
LI Ting;YANG Jun;ZHANG Tong;Shanghai University of Traditional Chinese Medicine;Xiangshan Hospital of Traditional Chinese Medicine;
..............page:2255-2261
Nano spray-dried powders for pulmonary drug delivery
XU En-yu;JIANG Jun-feng;XU Ying;WANG Yang;LI Hao-ying;School of Forensic Medicine;China Medical University;School of Chemistry and Chemical Engineering;Liaoning Normal University;Testing and Analysis Centre;Soochow University;School of Fundamental Sciences;China Medical University;Suzhou Huiren Biotech Co.;Ltd.;
..............page:2262-2267
Determination of memantine hydrochloride with pre-column derivatization HPLC
LOU Shu-han;WANG Dong;GU Xiao-tong;WANG Yi-fan;LI Xue-ming;School of Pharmaceutical Sciences;Nanjing University of Technology;
..............page:2268-2271
Case report and literature analysis of anaphylactic shock induced by succinylated gelatin
LIU Hong;SHI Rui;LI Ran;MA Xu;ZHANG Yan-hua;Key Laboratory of Carcinogenesis and Translational Research;Ministry of Education;Department of Pharmacy;Peking University Cancer Hospital & Institute;
..............page:2272-2276
Adefovir dipivoxil-induced Fanconi syndrome:a retrospective analysis of 77 cases
WANG Jun-na;HUANG Wen-xiang;Department of Infectious Diseases;the First Affiliated Hospital of Chongqing Medical University;
..............page:2277-2280