0513-4870
2016 Issue 8
Concise analysis for innovation of pioneering and follow-on drugs
GUO Zong-ru;Institute of Materia Medica;Chinese Academy of Medical Sciences and Peking Union Medical College;
GUO Zong-ru;Institute of Materia Medica;Chinese Academy of Medical Sciences and Peking Union Medical College;
..............page:1179-1184
Progress of clinical trials in Alzheimer’s disease drugs
PENG Ying;LI Ping-ping;LI Lin;ZHANG Yu;HOU Wei-zhen;CUI Dan-dan;LI Jiang;WANG Ling;WANG Qing-li;WANG Xiao-liang;Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study;Institute of Materia Medica;Chinese Academy of Medical Sciences and Peking Union Medical College;China National Center for Biotechnology Development;Center for Drug Evaluation;China Food and Drug Administration;
PENG Ying;LI Ping-ping;LI Lin;ZHANG Yu;HOU Wei-zhen;CUI Dan-dan;LI Jiang;WANG Ling;WANG Qing-li;WANG Xiao-liang;Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study;Institute of Materia Medica;Chinese Academy of Medical Sciences and Peking Union Medical College;China National Center for Biotechnology Development;Center for Drug Evaluation;China Food and Drug Administration;
..............page:1185-1195
..............page:1195
Advances in the study of the effect of basal forebrain on sleep-wake regulation
JIANG Shi-yu;WANG Lu;CHEN Li;HONG Zong-yuan;Institute of Quantitative Pharmacology;Wannan Medical College;Department of Pharmacology;Shanghai Medical College of Fudan University;Department of Neuronbiology;Shanghai Medical College of Fudan University;
JIANG Shi-yu;WANG Lu;CHEN Li;HONG Zong-yuan;Institute of Quantitative Pharmacology;Wannan Medical College;Department of Pharmacology;Shanghai Medical College of Fudan University;Department of Neuronbiology;Shanghai Medical College of Fudan University;
..............page:1196-1201
Absorption, distribution, metabolism, excretion and toxicity of biologics and its application in pharmacokinetic modeling
ZHANG Cui-feng;XIE Hai-tang;PAN Guo-yu;Wannan Medical College;Shanghai Institute of Materia Medica;Chinese Academy of Sciences;Yijishan Hospital of Wannan Medical College;
ZHANG Cui-feng;XIE Hai-tang;PAN Guo-yu;Wannan Medical College;Shanghai Institute of Materia Medica;Chinese Academy of Sciences;Yijishan Hospital of Wannan Medical College;
..............page:1202-1208
Antibody-drug conjugates: design and clinical progress
WANG Yu-jie;CAO Xin;LIU Xiao-yu;LU Xiao-ling;LI Yu-yan;JIAO Bing-hua;Department of Medicinal Chemistry;China Pharmaceutical University;Marine Biopharmaceutical Institute;Second Military Medical University;Department of Biochemistry and Molecular Biology;Second Military Medical University;Shanghai Institute of Organic Chemistry;Chinese Academy of Sciences;
WANG Yu-jie;CAO Xin;LIU Xiao-yu;LU Xiao-ling;LI Yu-yan;JIAO Bing-hua;Department of Medicinal Chemistry;China Pharmaceutical University;Marine Biopharmaceutical Institute;Second Military Medical University;Department of Biochemistry and Molecular Biology;Second Military Medical University;Shanghai Institute of Organic Chemistry;Chinese Academy of Sciences;
..............page:1209-1216
Application of modern mass spectrometry in metabolism and pharmacokinetics of traditional Chinese medicine
WANG Lu;PI Zi-feng;LIU Shu;LIU Zhi-qiang;SONG Feng-rui;National Center of Mass Spectrometry in Changchun;Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry;Changchun Institute of Applied Chemistry;Chinese Academy of Sciences;University of Chinese Academy of Sciences;
WANG Lu;PI Zi-feng;LIU Shu;LIU Zhi-qiang;SONG Feng-rui;National Center of Mass Spectrometry in Changchun;Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry;Changchun Institute of Applied Chemistry;Chinese Academy of Sciences;University of Chinese Academy of Sciences;
..............page:1217-1226
Progress in study of nitroimidazole as hypoxia imaging agents in tumor
YANG Yi-jun;DING Jing-song;School of Pharmaceutical Sciences;Central South University;
YANG Yi-jun;DING Jing-song;School of Pharmaceutical Sciences;Central South University;
..............page:1227-1232
The in vitro transport mechanism of bentysrepinine: a novel anti-hepatitis B virus drug candidate
FAN Hui-rong;CI Xiao-yan;LI Wei;ZENG Yong;YI Xiu-lin;SI Duan-yun;LIU Chang-xiao;LIANG Guang-yi;Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine;Institute of Radiation Medicine;Chinese Academy of Medical Sciences and Peking Union Medical College;State Key Laboratory of Drug Delivery Technology and Pharmacokinetics;Tianjin Institute of Pharmaceutical Research;The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences;
FAN Hui-rong;CI Xiao-yan;LI Wei;ZENG Yong;YI Xiu-lin;SI Duan-yun;LIU Chang-xiao;LIANG Guang-yi;Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine;Institute of Radiation Medicine;Chinese Academy of Medical Sciences and Peking Union Medical College;State Key Laboratory of Drug Delivery Technology and Pharmacokinetics;Tianjin Institute of Pharmaceutical Research;The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences;
..............page:1233-1239
Associations of SLCO1B1 polymorphisms with tacrolimus concentrations in Chinese renal transplant recipients
LIU Shu;CHEN Rong-xin;LI Jun;LIU Xiao-man;HUANG Hong-bing;FU Qian;WANG Chang-xi;HUANG Min;LI Jia-li;Cancer Center;State Key Laboratory of Oncology in South China;Collaborative Innovation Center for Cancer Medicine;Sun Yat-sen University;Institute of Clinical Pharmacology;School of Pharmaceutical Sciences;Sun Yat-sen University;State Key Laboratory of Ophthalmology;Zhongshan Ophthalmic Center;Sun Yat-sen University;Kidney Transplant Department;Transplant Center;The First Affiliated Hospital;Sun Yat-sen University;
LIU Shu;CHEN Rong-xin;LI Jun;LIU Xiao-man;HUANG Hong-bing;FU Qian;WANG Chang-xi;HUANG Min;LI Jia-li;Cancer Center;State Key Laboratory of Oncology in South China;Collaborative Innovation Center for Cancer Medicine;Sun Yat-sen University;Institute of Clinical Pharmacology;School of Pharmaceutical Sciences;Sun Yat-sen University;State Key Laboratory of Ophthalmology;Zhongshan Ophthalmic Center;Sun Yat-sen University;Kidney Transplant Department;Transplant Center;The First Affiliated Hospital;Sun Yat-sen University;
..............page:1240-1244
Establishment of a glioma orthotopic xenograft model based on imaging technology
JI Ming;WANG Li-yuan;Lü Yuan-hao;LAI Fang-fang;CHEN Xiao-guang;State Key Laboratory of Bioactive Substances and Functions of Natural Medicines;Institute of Materia Medica;Chinese Academy of Medical Sciences and Peking Union Medical College;
JI Ming;WANG Li-yuan;Lü Yuan-hao;LAI Fang-fang;CHEN Xiao-guang;State Key Laboratory of Bioactive Substances and Functions of Natural Medicines;Institute of Materia Medica;Chinese Academy of Medical Sciences and Peking Union Medical College;
..............page:1245-1249
..............page:1249
Synergistic anti-tumor effects of axitinib and doxorubicin
XU Xiu-li;HUANG Yuan;West China School of Pharmacy;Sichuan University;
XU Xiu-li;HUANG Yuan;West China School of Pharmacy;Sichuan University;
..............page:1250-1256
Evaluation of cryptotanshinone inhibition of angiogenesis in human hepatic sinusoidal endothelial cells
HUANG Kai;ZHAO Zhi-min;LIU Hong-liang;SUN Xin;Lü Jing;TAO Yan-yan;LIU Cheng-hai;Shanghai Key Laboratory of Traditional Chinese Clinical Medicine;Institute of Liver Diseases;Shuguang Hospital;Shanghai University of Traditional Chinese Medicine;E-institute of TCM Internal Medicine;Shanghai Municipal Education Commission;
HUANG Kai;ZHAO Zhi-min;LIU Hong-liang;SUN Xin;Lü Jing;TAO Yan-yan;LIU Cheng-hai;Shanghai Key Laboratory of Traditional Chinese Clinical Medicine;Institute of Liver Diseases;Shuguang Hospital;Shanghai University of Traditional Chinese Medicine;E-institute of TCM Internal Medicine;Shanghai Municipal Education Commission;
..............page:1257-1262
Establishment of vulnerable plaque model by mast cell activation in adventitia and evaluation of effectiveness of intervention of Shenlian tablet
LI Yu-jie;RUAN Cong-xiao;YANG Qing;WENG Xiao-gang;CHEN Ying;WANG Ya-jie;GUO Yan;ZHOU Bing-bing;LIU Si-si;JIANG Xiao-hui;ZHU Xiao-xin;Institute of Chinese Materia Medica;China Academy of Chinese Medical Sciences;
LI Yu-jie;RUAN Cong-xiao;YANG Qing;WENG Xiao-gang;CHEN Ying;WANG Ya-jie;GUO Yan;ZHOU Bing-bing;LIU Si-si;JIANG Xiao-hui;ZHU Xiao-xin;Institute of Chinese Materia Medica;China Academy of Chinese Medical Sciences;
..............page:1263-1270
Synthesis and antisense properties of 2’β-F- and 2’α-F-2’-deoxy-uridines modified oligonucleotides with 4’-C-(2-methoxyethoxy) substituent
MA Wei;WANG Jing;LU Dan-dan;YANG Jing;QIN Bing-jie;HE Xiao-yang;WANG Sheng-qi;Graduate School of Tianjin University of Traditional Chinese Medicine;Beijing Institute of Radiation Medicine;School of Pharmaceutical Sciences;Zhengzhou University;Beijing Institute of Pharmacology and Toxicology;
MA Wei;WANG Jing;LU Dan-dan;YANG Jing;QIN Bing-jie;HE Xiao-yang;WANG Sheng-qi;Graduate School of Tianjin University of Traditional Chinese Medicine;Beijing Institute of Radiation Medicine;School of Pharmaceutical Sciences;Zhengzhou University;Beijing Institute of Pharmacology and Toxicology;
..............page:1271-1280
A new biflavone from Dysosma versipellis
PENG Ling-fang;LU Li-he;YANG Li-guo;LU Xue-ping;CUI Tao;ZHU Zhao-yun;Yunnan Institute of Materia Medica;Innovation and R&D Center of Yunnan Bai Yao Group;
PENG Ling-fang;LU Li-he;YANG Li-guo;LU Xue-ping;CUI Tao;ZHU Zhao-yun;Yunnan Institute of Materia Medica;Innovation and R&D Center of Yunnan Bai Yao Group;
..............page:1281-1284
A new anti-hypoxia sesquiterpene from the rhizome of Petasites japonicus
XIE Yao-yu;LI Yu-xian;SUN Yi-ming;WANG Yan;GUO Mei-li;School of Pharmacy;Second Military Medical University;Department of Plant Science;Jilin Agricultural Science and Technology College;Department of Pharmacy;Shanghai Putuo District Liqun Hospital;
XIE Yao-yu;LI Yu-xian;SUN Yi-ming;WANG Yan;GUO Mei-li;School of Pharmacy;Second Military Medical University;Department of Plant Science;Jilin Agricultural Science and Technology College;Department of Pharmacy;Shanghai Putuo District Liqun Hospital;
..............page:1285-1289
Bioactive consistency evaluation of cardiotonic pill using marker genes
SUN Wan-yang;TONG Ling;LI Dong-xiang;BI Kai-shun;Department of Pharmaceutical Analysis;Shenyang Pharmaceutical University;State Key laboratory of Core Technology in Innovative Chinese Medicine;Tasly Pharmaceutical Analysis Institute;Tasly Academy;
SUN Wan-yang;TONG Ling;LI Dong-xiang;BI Kai-shun;Department of Pharmaceutical Analysis;Shenyang Pharmaceutical University;State Key laboratory of Core Technology in Innovative Chinese Medicine;Tasly Pharmaceutical Analysis Institute;Tasly Academy;
..............page:1290-1296
Chiral separation of fourteen amino alcohols by nonaqueous capillary electrophoresis
AN Ning;WANG Li-juan;Lü Li-li;FU Jian-nan;WANG Yu-fei;ZHAO Jing-jing;GUO Huai-zhong;Key Laboratory of Pharmaceutical Quality Control of Hebei Province;College of Pharmaceutical Sciences;Hebei University;
AN Ning;WANG Li-juan;Lü Li-li;FU Jian-nan;WANG Yu-fei;ZHAO Jing-jing;GUO Huai-zhong;Key Laboratory of Pharmaceutical Quality Control of Hebei Province;College of Pharmaceutical Sciences;Hebei University;
..............page:1297-1301
Chemical constituents and mechanism of Corydalis Rhizoma based on HPLC-QTOF/MS and G protein-coupled receptor analysis
HAN Yan-qi;XU Jun;GONG Su-xiao;ZHANG Tie-jun;LIU Chang-xiao;Tianjin Engineering Laboratory of Quality Control Technology of Traditional Chinese Medicine;Tianjin Institute of Pharmaceutical Research;Tianjin Center for New Drug Evaluation and Research;State Key Laboratory of Drug Delivery Technology and Pharmacokinetics;Tianjin Institute of Pharmaceutical Research;
HAN Yan-qi;XU Jun;GONG Su-xiao;ZHANG Tie-jun;LIU Chang-xiao;Tianjin Engineering Laboratory of Quality Control Technology of Traditional Chinese Medicine;Tianjin Institute of Pharmaceutical Research;Tianjin Center for New Drug Evaluation and Research;State Key Laboratory of Drug Delivery Technology and Pharmacokinetics;Tianjin Institute of Pharmaceutical Research;
..............page:1302-1308
..............page:1308
Preparation and quality evaluation of comet-shaped hydroxy camptothecin-loaded amphiphilic block copolymer
XIE Li-ya;CHANG Di;HOU Zhen-qing;YANG Xiang-rui;HAN Ding;First Affiliated Hospital of Xiamen University;Research Center of Biomedical Engineering of Xiamen University;
XIE Li-ya;CHANG Di;HOU Zhen-qing;YANG Xiang-rui;HAN Ding;First Affiliated Hospital of Xiamen University;Research Center of Biomedical Engineering of Xiamen University;
..............page:1309-1315
The integrity study on PEG-PCL micelles transcellular transported across MDCK epithelial cell monolayer using FRET technology
LI Rui;SONG Xiao-ning;ZHANG Hua;DAI Wen-bing;HE Bing;ZHENG Ying;ZHANG Qiang;WANG Xue-qing;Department of Pharmaceutics;School of Pharmaceutical Sciences;Peking University;State Key Laboratory of Quality Research in Chinese Medicine;Institute of Chinese Medical Sciences;University of Macau;
LI Rui;SONG Xiao-ning;ZHANG Hua;DAI Wen-bing;HE Bing;ZHENG Ying;ZHANG Qiang;WANG Xue-qing;Department of Pharmaceutics;School of Pharmaceutical Sciences;Peking University;State Key Laboratory of Quality Research in Chinese Medicine;Institute of Chinese Medical Sciences;University of Macau;
..............page:1316-1324
Rhizosphere microorganism evidence on geo-authentic features of traditional Chinese medicine from Moutan(Paeonia suffruticosa)
ZHENG Yan;LIU Wei;HUANG Jun-xiang;HOU Yu-rong;College of Life Sciences;Institute of Traditional Chinese Medicine Resources;Anhui Normal University;Anhui Provincial Engineering Technology Research Center of Traditional Chinese Medicine Daily Supplies;
ZHENG Yan;LIU Wei;HUANG Jun-xiang;HOU Yu-rong;College of Life Sciences;Institute of Traditional Chinese Medicine Resources;Anhui Normal University;Anhui Provincial Engineering Technology Research Center of Traditional Chinese Medicine Daily Supplies;
..............page:1325-1333
Molecular cloning and characterization of the 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene from Artemisia annua L.
ZHANG Man;XIANG Li-en;WANG Hui;LAN Xiao-zhong;CHEN Min;LIAO Zhi-hua;School of Life Sciences;Southwest University;SWU-TAAHC Medicinal Plant Joint R&D Centre;Medicinal Plants Research Centre;Agriculture and Animal Husbandry College;Tibet University;College of Pharmaceutical Sciences;Southwest University;
ZHANG Man;XIANG Li-en;WANG Hui;LAN Xiao-zhong;CHEN Min;LIAO Zhi-hua;School of Life Sciences;Southwest University;SWU-TAAHC Medicinal Plant Joint R&D Centre;Medicinal Plants Research Centre;Agriculture and Animal Husbandry College;Tibet University;College of Pharmaceutical Sciences;Southwest University;
..............page:1334-1339
Preparation of doxorubicin-loaded Fe3O4-TiO2 nanoparticles and evaluation of chemo-photodynamic therapy in vivo
HU Yu-ping;ZHOU Hai-yun;SHEN Song;Hangzhou Third People’s Hospital;Second Affiliated Hospital of Zhejiang University;College of Pharmaceutical Sciences;Jiangsu University;
HU Yu-ping;ZHOU Hai-yun;SHEN Song;Hangzhou Third People’s Hospital;Second Affiliated Hospital of Zhejiang University;College of Pharmaceutical Sciences;Jiangsu University;
..............page:1340-1344
..............page:1344
ji yu zuo yong ji zhi yan zhi de lei te ge wei
guo zong ru ;
guo zong ru ;
..............page:1345-1348