Acute appendicitis: What is the gold standard of treatment?
Cesare Ruffolo;Alain Fiorot;Giulia Pagura;Michele Antoniutti;Marco Massani;Ezio Caratozzolo;Luca Bonariol;Francesco Calia di Pinto;Nicolò Bassi;Ⅱ Deparment of Surgery;Regional Hospital "Ca’ Foncello";31100 Treviso;Italy;

..............page:8799-8807

Surveillance for early diagnosis of hepatocellular carcinoma: How best to do it?
Edoardo G Giannini;Alessandro Cucchetti;Virginia Erroi;Francesca Garuti;Federica Odaldi;Franco Trevisani;Dipartimento di Medicina Interna;Unità di Gastroenterologia;Università di Genova;IRCCS-Azienda Ospedaliera San Martino-IST;16155 Genova;Italy;Dipartimento di Scienze Mediche Chirurgiche;Unità di Chirurgia Generale e dei Trapianti;40138 Bologna;Italy;Dipartimento di Scienze Mediche Chirurgiche;Unità di Semeiotica Medica;Alma Mater Studiorum-Università di Bologna;40138 Bologna;Italy;

..............page:8808-8821

Hepatocellular carcinoma in chronic hepatitis B patients under antiviral therapy
John Vlachogiannakos;George Papatheodoridis;Academic Department of Gastroenterology;Athens University Medical School;Laiko General Hospital;11527 Athens;Greece;

..............page:8822-8830

Hierarchical and selective roles of galectins in hepatocarcinogenesis,liver fibrosis and inflammation of hepatocellular carcinoma
María L Bacigalupo;Malena Manzi;Gabriel A Rabinovich;María F Troncoso;Institute of Biological Chemistry and Biophysics "Prof. Alejandro C. Paladini";Department of Biological Chemistry;School of Pharmacy and Biochemistry;University of Buenos Aires;C1113AAD;Buenos Aires;Argentina;Institute of Biology and Experimental Medicine;Department of Biological Chemistry;School of Exact and Natural Sciences;University of Buenos Aires;C1113AAD Buenos Aires;Argentina;

..............page:8831-8849

Cellular reprogramming and hepatocellular carcinoma development
Yun-Wen Zheng;Yun-Zhong Nie;Hideki Taniguchi;Department of Regenerative Medicine;Graduate School of Medicine;Yokohama City University;Kanazawa-ku;Yokohama;Kanagawa 236-0004;Japan;Jiangsu University Hospital;Advanced Medical Research Center;Yokohama City University;Yokohama;Kanagawa 236-0004;Japan;

..............page:8850-8860

Anti-viral therapy to reduce recurrence and improve survival in hepatitis B virus-related hepatocellular carcinoma
Toru Ishikawa;Department of Gastroenterology and Hepatology;Saiseikai Niigata Daini Hospital;Niigata 950-1104;Japan;

..............page:8861-8866

Risk prediction of hepatitis B virus-related hepatocellular carcinoma in the era of antiviral therapy
Il Han Song;So Mi Kim;Young Kwang Choo;Division of Hepatology;Department of Internal Medicine;Dankook University College of Medicine;Cheonan 330-715;South Korea;Department of Internal Medicine;Jeju National University School of Medicine;Jeju 690-767;South Korea;

..............page:8867-8872

Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma
De-Leung Gu;Yen-Hsieh Chen;Jou-Ho Shih;Chi-Hung Lin;Yuh-Shan Jou;Chian-Feng Chen;Institute of Biomedical Sciences;Academia Sinica;Institute of Microbiology and Immunology;School of Life Science;National Yang-Ming University;Bioinformatics Program;Taiwan International Graduate Program;Academia Sinica;Genome and Systems Biology Degree Program;National Taiwan University;VYM Genome Research Center;National Yang-Ming University;

..............page:8873-8879

Mitochondrial DNA alterations and mitochondrial dysfunction in the progression of hepatocellular carcinoma
Chia-Chi Hsu;Hsin-Chen Lee;Yau-Huei Wei;Institute of Pharmacology;School of Medicine;National Yang-Ming University;Department of Biochemistry and Molecular Biology;National Yang-Ming University;Department of Medicine;Mackay Medical College;

..............page:8880-8886

Prevention of hepatocellular carcinoma in chronic viral hepatitis B and C infection
Tao Lu;Wai-Kay Seto;Ran-Xu Zhu;Ching-Lung Lai;Man-Fung Yuen;Department of Medicine;The University of Hong Kong-Shenzhen Hospital;Department of Medicine;The University of Hong Kong;Queen Mary Hospital;

..............page:8887-8894

Effects of antiviral therapy on preventing liver tumorigenesis and hepatocellular carcinoma recurrence
Zhong-Ming Tan;Bei-Cheng Sun;Liver Transplantation Center of the First Affiliated Hospital;Nanjing Medical University;The Key Laboratory of Living Donor Liver Transplantation;Ministry of Health;

..............page:8895-8901

Exploitation of host clock gene machinery by hepatitis viruses B and C
Manlio Vinciguerra;Gianluigi Mazzoccoli;Claudia Piccoli;Tiziana Tataranni;Angelo Andriulli;Valerio Pazienza;Institute for Liver and Digestive Health;Division of Medicine;University College London;London SW7 2AZ;United Kingdom;Gastroenterology Unit;IRCCS "Casa Sollievo della Sofferenza" Hospital;71013 San Giovanni Rotondo;Italy;Department of Medical Sciences;Division of Internal Medicine;IRCCS Scientific Institute and Regional General Hospital "Casa Sollievo della Sofferenza";71013 San Giovanni Rotondo;Italy;Department of Clinical and Experimental Medicine;University of Foggia;71100 Foggia;Italy;Laboratory of Pre-Clinical and Translational Research;IRCCS;Centro di Riferimento Oncologico della Basilicata;85028 Rionero in Vulture;Italy;

..............page:8902-8909

Hepatitis C virus-related mixed cryoglobulinemia: Is genetics to blame?
Laura Gragnani;Elisa Fognani;Alessia Piluso;Anna Linda Zignego;Center for Systemic Manifestations of Hepatitis Viruses;Department of Experimental and Clinical Medicine;University of Florence;50134 Florence;Italy;

..............page:8910-8915

Immunological alterations in hepatitis C virus infection
Vincenza Calvaruso;Antonio Craxì;Gastroenterologia and Epatologia;DIBIMIS;Università di Palermo;90127 Palermo;Italy;

..............page:8916-8923

Interleukin 28B polymorphisms as predictor of response in hepatitis C virus genotype 2 and 3 infected patients
Alessandra Mangia;Leonardo Mottola;Rosanna Santoro;Liver Unit-IRCCS;"Casa Sollievo della Sofferenza";San Giovanni Rotondo;71013 FG;Italy;

..............page:8924-8928

Post-translational modifications of hepatitis C viral proteins and their biological significance
Jana Hundt;Zhubing Li;Qiang Liu;Vaccine and Infectious Disease Organization-International Vaccine Center;University of Saskatchewan;Saskatoon;SK S7N 5E3;Canada;

..............page:8929-8939

Hepatitis C virus protease inhibitor-resistance mutations: Our experience and review
Shuang Wu;Tatsuo Kanda;Shingo Nakamoto;Fumio Imazeki;Osamu Yokosuka;Department of Gastroenterology and Nephrology;Chiba University;Graduate School of Medicine;Chiba 260-8677;Japan;Postdoctoral Fellow;Foreign Researcher of the Japan Society for Promotion of Science;Tokyo 102-0083;Japan;Department of Molecular Virology;Chiba University;Graduate School of Medicine;Chiba 260-8677;Japan;Safety and Health Organization;Chiba University;Chiba 263-8522;Japan;

..............page:8940-8948

Prospects for nucleic acid-based therapeutics against hepatitis C virus
Chang Ho Lee;Ji Hyun Kim;Seong-Wook Lee;Department of Molecular Biology;Institute of Nanosensor and Biotechnology;Dankook University;Yongin 448-701;South Korea;

..............page:8949-8962

Antiviral treatment of hepatitis C virus infection and factors affecting efficacy
Yan Zhu;Song Chen;Institute of Infectious Diseases;Southwest Hospital;the Third Military Medical University;

..............page:8963-8973

Extra-intestinal and long term consequences of Giardia duodenalis infections
Marie CM Halliez;André G Buret;Department of Biological Sciences;Inflammation Research Network;University of Calgary;Calgary;Alberta;AB T2N 1N4;Canada;Parasitology Department;Rouen University Hospital & EA 3800;Institute for Biomedical & Research;University of Rouen;Rouen;76183;France;

..............page:8974-8985

Non-microbial approach for Helicobacter pylori as faster track to prevent gastric cancer than simple eradication
Sang-Ho Park;Napapan Kangwan;Jong-Min Park;Eun-Hee Kim;Ki Baik Hahm;CHA Cancer Prevention Research Center;CHA Cancer Institute;CHA University;Seoul 135-081;South Korea;

..............page:8986-8995

Digestive cancer surgery in the era of sentinel node and epithelial-mesenchymal transition
Nadia Peparini;Azienda Sanitaria Locale Roma H;via Mario Calo’ 5 - 00043 Ciampino;Italy;Italy;

..............page:8996-9002

Pancreatic trauma: A concise review
Uma Debi;Ravinder Kaur;Kaushal Kishor Prasad;Saroj Kant Sinha;Anindita Sinha;Kartar Singh;Division of GE Radiology;Department of Superspeciality of Gastroenterology;Postgraduate Institute of Medical Education and Research;Chandigarh 160 012;India;Department of Radiodiagnosis;Government Medical College and Hospital;Chandigarh 160 012;India;Division of GE Histopathology;Department of Superspeciality of Gastroenterology;Postgraduate Institute of Medical Education and Research;Chandigarh 160 012;India;Department of Superspeciality of Gastroenterology;Postgraduate Institute of Medical Education and Research;Chandigarh 160 012;India;Department of Radiodiagnosis;Postgraduate Institute of Medical Education and Research;Chandigarh 160 012;India;

..............page:9003-9011

Clinically detected gastroenteropancreatic neuroendocrine tumors are on the rise: Epidemiological changes in Germany
Hans Scherübl;Brigitte Streller;Roland Stabenow;Hermann Herbst;Michael Hpfner;Christoph Schwertner;Joachim Steinberg;Jan Eick;Wanda Ring;Krishna Tiwari;Sren M Zappe;Klinik für Gastroenterologie;GI Onkologie und Infektiologie;Vivantes Klinikum Am Urban;10967 Berlin;Germany;Gemeinsames Krebsregister der L?nder Berlin;Brandenburg;Mecklenburg-Vorpommern;Sachsen-Anhalt und der Freistaaten Sachsen und Thüringen;10967 Berlin;Germany;Institut für Pathologie;Vivantes Netzwerk für Gesundheit GmbH;10967 Berlin;Germany;Institut für Physiologie;Charité-Universit?tsmedizin;10117 Berlin;Germany;Charité-Universit?tsmedizin Berlin;HNO-Klinik;Campus Virchow Klinikum;13353 Berlin;Germany;

..............page:9012-9019

Nrf2 and Snail-1 in the prevention of experimental liver fibrosis by caffeine
Daniela Gordillo-Bastidas;Edén Oceguera-Contreras;Adriana Salazar-Montes;Jaime González-Cuevas;Luis Daniel Hernández-Ortega;Juan Armendáriz-Borunda;nstitute of Molecular Biology in Medicine and Gene Therapy/CUCS;University of Guadalajara;Guadalajara;Jalisco 44100;México;

..............page:9020-9033

Superficial esophageal lesions detected by endoscopic ultrasound enhanced with submucosal edema
Jian-Jun Li;Long-Jun He;Hong-Bo Shan;Thomas D Wang;Huan Xiong;Li-Ming Chen;Guo-Liang Xu;Xiao-Hai Li;Xin-Xin Huang;Guang-Yu Luo;Yin Li;Rong Zhang;Department of Endoscopy;Sun Yat-sen University Cancer Center;State Key Laboratory of Oncology in South China;Collaborative Innovation Center for Cancer Medicine;Division of Gastroenterology;University of Michigan;Ann Arbor;MI 48109;United States;Department of Medical Record Statistics;The First Affiliated Hospital;Sun Yat-sen University;Department of Cardiothoracic Surgery;The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine;

..............page:9034-9042

Small bowel tumors detected and missed during capsule endoscopy: Single center experience
Edyta S Zagorowicz;Anna M Pietrzak;Ewa Wronska;Jacek Pachlewski;Piotr Rutkowski;Ewa Kraszewska;Jaroslaw Regula;Department of Gastroenterology;The Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology;02-781 Warsaw;Poland;Department of Gastroenterology and Hepatology;Medical Center for Postgraduate Education;01-813 Warsaw;Poland;Department of Soft Tissue/Bone Sarcoma and Melanoma;The Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology;02-781 Warsaw;Poland;

..............page:9043-9048

Serum concentrations of insulin-like growth factor-binding protein 5 in Crohn’s disease
Gupse Adali;Elif Yorulmaz;Seyma Ozkanli;Celal Ulasoglu;Baris Bayraktar;Alev Orhun;Yasar Colak;Ilyas Tuncer;Department of Gastroenterology;Goztepe Training and Research Hospital;Istanbul Medeniyet University;Doktor Erkin Caddesi Kadikoy;Istanbul 34730;Turkey;Department of Pathology;Goztepe Training and Research Hospital;Istanbul Medeniyet University;Doktor Erkin Caddesi Kadikoy;Istanbul 34730;Turkey;Department of General Surgery;Goztepe Training and Research Hospital;Istanbul Medeniyet University;Doktor Erkin Caddesi Kadikoy;Istanbul 34730;Turkey;Department of Biochemistry;Goztepe Training and Research Hospital;Istanbul Medeniyet University;Doktor Erkin Caddesi Kadikoy;Istanbul 34730;Turkey;

..............page:9049-9056

Alvarado,Eskelinen,Ohhmann and Raja Isteri Pengiran Anak Saleha Appendicitis scores for diagnosis of acute appendicitis
Hasan Erdem;Süleyman etinkünar;Koray Das;Enver Reyhan;Cumhur Deger;Mehmet Aziret;Hilmi Bozkurt;Seluk Uzun;Selim Szen;Oktay rkrücü;Department of General Surgery;Adana Numune Training and Research Hospital;Adana 01240;Turkey;

..............page:9057-9062

Seasonal variations in the onset of ulcerative colitis in Japan
Shigeo Koido;Toshifumi Ohkusa;Hiroaki Saito;Tetsuji Yokoyama;Tomoyoshi Shibuya;Naoto Sakamoto;Kan Uchiyama;Hiroshi Arakawa;Taro Osada;Akihito Nagahara;Sumio Watanabe;Hisao Tajiri;Division of Gastroenterology and Hepatology;Department of Internal Medicine;the Jikei University School of Medicine;Chiba 277-8567;Japan;Department of Gastroenterology;Juntendo University School of Medicine;Tokyo 113-8421;Japan;Department of Health Promotion;National Institute of Public Health;Saitama 351-0197;Japan;

..............page:9063-9068

Anxiety and depression propensities in patients with acute toxic liver injury
Jeong Ill Suh;Jeong Kyu Sakong;Kwan Lee;Yong Kook Lee;Jeong Bae Park;Dong Joon Kim;Yeon Seok SeoDepartment of Internal Medicine;Korea University Anam Hospital;Korea University College of Medicine;Seoul 136-705;South Korea;Jae Dong Lee;Soon Young Ko;Byung Seok Lee;Seok Hyun Kim;Byung Seok Kim;Young Seok Kim;Heon Ju Lee;In Hee Kim;Joo Hyun Sohn;Tae Yeob Kim;Byung Min Ahn;Department of Internal Medicine;Dongguk University Gyeongju Hospital;Dongguk University College of Medicine;Gyeongju 780-350;South Korea;Department of Psychiatry;Dongguk University Gyeongju Hospital;Dongguk University College of Medicine;Gyeongju 780-350;South Korea;Department of Preventive Medicine;Dongguk University College of Medicine;Gyeongju 780-350;South Korea;Department of Internal Medicine;Hallym University Medical Center;Hallym University College of Medicine;Chuncheon 200-704;South Korea;Department of Internal Medicine;Konkuk University Chungju Hospital;Konkuk University College of Medicine;Chungju 380-704;South Korea;Department of Internal Medicine;Chungnam National University Hospital;Chungnam University College of Medicine;Daejeon 301-721;South Korea;Department of Internal Medicine;Daegu Catholic University Medical Center;Daegu Catholic University College of Medicine;Daegu 705-718;South Korea;Department of Internal Medicine;Soonchunhyang University Bucheon Hospital;Soonchunhyang University College of Medicine;Bucheon 420-767;South Korea;Department of Internal Medicine;Yeungnam University Medical Center;Yeungnam University College of Medicine;Daegu 705-703;South Korea;Department of Internal Medicine;Chonbuk National University Hospital;Chonbuk National University College of Medicine;Jeonju 561-712;South Korea;Department of Internal Medicine;Hanyang University Guri Hospital;Hanyang University College of Medicine;Guri 471-701;South Korea;Department of Internal Medicine;Hwain Metro Hospital;Chunan 331-959;South Korea;

..............page:9069-9076

Appropriateness,endoscopic findings and contributive yield of pediatric gastrointestinal endoscopy
Way Seah Lee;Hafizah Zainuddin;Christopher CM Boey;Pei Fan Chai;Department of Paediatrics;University Malaya Medical Centre;50603 Kuala Lumpur;Malaysia;University Malaya Paediatrics and Child Health Research Group;University Malaya;50603 Kuala Lumpur;Malaysia;Department of Paediatrics;Faculty of Medicine;University Technology Mara;40450 Selayang;Selangor;Malaysia;

..............page:9077-9083

Routine lymph node dissection may be not suitable for all intrahepatic cholangiocarcinoma patients: Results of a monocentric series
Dong-Yu Li;Hai-Bin Zhang;Ning Yang;Yuan Quan;Guang-Shun Yang;Fifth Department of Hepatic Surgery;Eastern Hepatobiliary Surgery Hospital;Second Military Medical University;

..............page:9084-9091

Separate calculation of DW-MRI in assessing therapeutic effect in liver tumors in rats
Feng Chen;Frederik De Keyzer;Yuan-Bo Feng;Marlein Miranda Cona;Jie Yu;Guy Marchal;Raymond Oyen;Yi-Cheng Ni;Department of Radiology;the First Affiliated Hospital;College of Medicine;Zhejiang University;Department of Imaging and Pathology;University Hospital;University of Leuven;Herestraat 49;Bus 7003;3000 Leuven;Belgium;

..............page:9092-9103

¹³¹ I-labeled metuximab combined with chemoembolization for unresectable hepatocellular carcinoma
Qing He;Wu-Sheng Lu;Yang Liu;Yong-Song Guan;An-Ren Kuang;Oncology Department;West China Hospital of Sichuan University;Department of Vascular Surgery;West China Hospital of Sichuan University;Department of Psychiatry;West China Hospital of Sichuan University;Department of Nuclear Medicine;West China Hospital of Sichuan University;

..............page:9104-9110

Efficacy of mosapride plus proton pump inhibitors for treatment of gastroesophageal reflux disease: A systematic review
Qing Liu;Chen-Chen Feng;Er-Man Wang;Xiu-Juan Yan;Sheng-Liang Chen;Department of Gastroenterology;Ren Ji Hospital;School of Medicine;Shanghai Institute of Digestive Disease;Shanghai Jiao Tong University;

..............page:9111-9118

Fast-track rehabilitation vs conventional care in laparoscopic colorectal resection for colorectal malignancy: A meta-analysis
Ping Li;Fang Fang;Jia-Xun Cai;Dong Tang;Qing-Guo Li;Dao-Rong Wang;Department of Gastrointestinal Surgery;Subei People’s Hospital of Jiangsu Province;the First Affiliated Hospital of Yang Zhou University;Department of Colorectal Surgery;Cancer Hospital Fudan University;Department of Oncology;Shanghai Medical College;Fudan University;

..............page:9119-9126

Localized type 1 autoimmune pancreatitis superimposed upon preexisting intraductal papillary mucinous neoplasms
Takahiro Urata;Yoshiki Naito;Yoshihiro Izumi;Yoshi Takekuma;Hiroshi Yokomizo;Michiko Nagamine;Seiji Fukuda;Kenji Notohara;Michio Hifumi;Department of Gastroenterology;Japanese Red Cross Kumamoto Hospital;Kumamoto 861-8520;Japan;Department of Pathology;Kurume University School of Medicine;Kurume City;Fukuoka 830-0011;Japan;Department of Surgery;Japanese Red Cross Kumamoto Hospital;Kumamoto 861-8520;Japan;Department of Pathology;Japanese Red Cross Kumamoto Hospital;Kumamoto 861-8520;Japan;Department of Anatomic Pathology;Kurashiki Central Hospital;Kurashiki City;Okayama 701-01;Japan;

..............page:9127-9132

DOG1 is useful for diagnosis of KIT-negative gastrointestinal stromal tumor of stomach
Takuya Wada;Satoshi Tanabe;Kenji Ishido;Katsuhiko Higuchi;Tohru Sasaki;Chikatoshi Katada;Mizutomo Azuma;Akira Naruke;Myunguchul Kim;Wasaburo Koizumi;Tetsuo Mikami;Department of Gastroenterology;Kitasato University East Hospital;Kanagawa 252-0380;Japan;Department of Pathology;Kitasato University East Hospital;Kanagawa 252-0380;Japan;

..............page:9133-9136

Assessment of proximal gastric accommodation in patients with functional dyspepsia
Paola Iovino;Antonella Santonicola;Carolina Ciacci;Gastrointestinal Unit;Department of Medicine and Surgery;University of Salerno;84081 Salerno;Italy;Department of Clinical Medicine and Surgery;University Federico Ⅱ of Naples;80131 Naples;Italy;

..............page:9137-9138

INSTRUCTIONS TO AUTHORS

..............page:9139-9144