1672-173X
2014 Issue 1
Identification and Functional Analysis of a Testis-specific E3 Ubiquitin Ligase Gene Rnf148 in Mouse
LIU Yun-qiang;TAO Da-chang;LIAO Shun-yao;YANG Yuan;MA Yong-xin;ZHANG Si-zhong;Department of Medical Genetics & Division of Human Morbid Genomics;State Key Laboratory of Biotherapy;West China Hospital;Sichuan University;Institute of Organ Transplantation;Sichuan Academy of Medical Science;Sichuan Provincial People’s Hospital;
LIU Yun-qiang;TAO Da-chang;LIAO Shun-yao;YANG Yuan;MA Yong-xin;ZHANG Si-zhong;Department of Medical Genetics & Division of Human Morbid Genomics;State Key Laboratory of Biotherapy;West China Hospital;Sichuan University;Institute of Organ Transplantation;Sichuan Academy of Medical Science;Sichuan Provincial People’s Hospital;
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The Profile of IGF2R Gene Expression and H3 Histone Modifications in Replicative Cell Senescence
XU Wei;ZHUANG Zhi-xiong;YANG Jian-ping;YANG Lin-qing;XU Yu-ling;ZHANG Wen-juan;ZENG Yi1·;Sichuan Center for Disease Control and Prevention;Shenzhen Center for Disease Control and Prevention;
XU Wei;ZHUANG Zhi-xiong;YANG Jian-ping;YANG Lin-qing;XU Yu-ling;ZHANG Wen-juan;ZENG Yi1·;Sichuan Center for Disease Control and Prevention;Shenzhen Center for Disease Control and Prevention;
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Stable Expression of Human Thyrotropin Receptor in HEK 293T Cells
TANG Gong-shun;Department of Nuclear Medicine;West China Hospital;Sichuan University;
TANG Gong-shun;Department of Nuclear Medicine;West China Hospital;Sichuan University;
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Study on the Anti-apoptosis Effect of Insulin-like Growth FactorⅠ on the Regulation of Neural Precursor Cells Survival
TANG Mei;WANG Qi;LI He-dong;YANG Fan;Department of Pediatrics;West China Second Hospital;Sichuan University;Department of Stem Cell Institute;West China Second Hospital;Sichuan University;
TANG Mei;WANG Qi;LI He-dong;YANG Fan;Department of Pediatrics;West China Second Hospital;Sichuan University;Department of Stem Cell Institute;West China Second Hospital;Sichuan University;
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Effects of Jianpi Qinghua Decoctions on Immune Inflammatory Injury in Adriamycin-induced Nephropathic Rats
MA Xiao-hong;HE Li-qun;Department of Urology;Shuguang Hospital;Shanghai University of Traditional Chinese Medicine;Clinical Key Laboratory of Traditional Chinese Medicine;Shanghai University of Traditional Chinese Medicine;
MA Xiao-hong;HE Li-qun;Department of Urology;Shuguang Hospital;Shanghai University of Traditional Chinese Medicine;Clinical Key Laboratory of Traditional Chinese Medicine;Shanghai University of Traditional Chinese Medicine;
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The Protective Effects of Rosiglitazone on Kidney in Diet-induced Obese Rats
SUN Xiao-dong;YU Ye-rong;Department of Endocrinology and Metabolism;West China Hospital;Sichuan University;
SUN Xiao-dong;YU Ye-rong;Department of Endocrinology and Metabolism;West China Hospital;Sichuan University;
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Human Umbilic Mesenchymal Stronmal Cells Repairs Diabetic Foot in Rats Associated with VEGF Expressional Change
WANG Ying;DAN Qi-qin;WANG Qing-ping;ZHOU Ning;JIN Xing-fang;HOU Zong-liu;PENG Bao-kun;WANG Ting-hua;Yan-an Hospital Affiliated to Kunming Medical University;Institute of Neuroscience;Kunming Medical University;Translational Neuroscience Center;West China Hospital;Sichuan University;
WANG Ying;DAN Qi-qin;WANG Qing-ping;ZHOU Ning;JIN Xing-fang;HOU Zong-liu;PENG Bao-kun;WANG Ting-hua;Yan-an Hospital Affiliated to Kunming Medical University;Institute of Neuroscience;Kunming Medical University;Translational Neuroscience Center;West China Hospital;Sichuan University;
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Management of Chronic Kidney Disease Guided by the Theory of Traditional Chinese Medicine:an Experimental Study
WEN Ji;XIE Xi-sheng;ZHANG Ming-hua;MAO Nan;ZHANG Cheng-long;XIE Lin-shen;CHENG Yuan;ZHANG Zi-yuan;FAN Jun-ming;Department of Nephrology;West China Hospital;Sichuan University;Department of Nephrology;Nanchong Central Hospital;Luzhou Medical College;
WEN Ji;XIE Xi-sheng;ZHANG Ming-hua;MAO Nan;ZHANG Cheng-long;XIE Lin-shen;CHENG Yuan;ZHANG Zi-yuan;FAN Jun-ming;Department of Nephrology;West China Hospital;Sichuan University;Department of Nephrology;Nanchong Central Hospital;Luzhou Medical College;
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Protective Effects of Hydrogen on Renal Ischemia/Reperfusion Injury in Rats
ZENG Kui;HUANG Han;JIANG Xiao-qin;CHEN Xiao-jing;HUANG Wei;Department of Anesthesiology;West China Second Hospital;Sichuan University;
ZENG Kui;HUANG Han;JIANG Xiao-qin;CHEN Xiao-jing;HUANG Wei;Department of Anesthesiology;West China Second Hospital;Sichuan University;
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The Expression of KAI1 in Gastric Adenocarcinoma and Relationship with Angiogenesis/Lymphangiogenesis
ZHOU Lei;WU Shi-wu;YU Lan;SONG Wen-qing;CHENG Ze-nong;WANG Dan-na;Department of Pathology;the First Affiliated Hospital of Bengbu Medical College;Bengbu Medical College;
ZHOU Lei;WU Shi-wu;YU Lan;SONG Wen-qing;CHENG Ze-nong;WANG Dan-na;Department of Pathology;the First Affiliated Hospital of Bengbu Medical College;Bengbu Medical College;
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Relationship of IFRD1-rs3807213 Gene Polymorphism with the Risk of Gastric Cancer among Chinese
PENG Chang-bing;XU Rui;XIAO Shuo-meng;ZHUANG Wen;Department of Gastrointestinal Surgery;West China Hospital;Sichuan University;Department of Gastrointestinal Surgery;Sichuan Cancer Hospital;
PENG Chang-bing;XU Rui;XIAO Shuo-meng;ZHUANG Wen;Department of Gastrointestinal Surgery;West China Hospital;Sichuan University;Department of Gastrointestinal Surgery;Sichuan Cancer Hospital;
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jing ji dian tu zhen duan tang niao bing xing ji wei suo zheng 1 li bao gao
xie dan dan ; zeng yan ;
xie dan dan ; zeng yan ;
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Study on the Correlation Factors on CD44+CD24-/low ESA+Lin- Cell Ratio in Breast Cancer
WANG Rong;YANG Xiao-qin;L Qing;Department of Thyroid & Breast Surgery;West China Hospital;Department of Breast Surgery;the Affiliated Hospital of Guiyang Medical College;
WANG Rong;YANG Xiao-qin;L Qing;Department of Thyroid & Breast Surgery;West China Hospital;Department of Breast Surgery;the Affiliated Hospital of Guiyang Medical College;
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Study of Molecular Epidemiology and Genetic Diversity of Human Bocvirus in Children with Respiratory Tract Infection in Sichuan
YANG Jing-yan;HU Peng-wei;CHEN Rui;LU Lei;PEI Xiao-fang;Department of Medical Technology;West China School of Public Health;Sichuan University;Department of Microbiology and Immunology Technology;School of Medical Technology;Chengdu University of Traditional Chinese Medicine;
YANG Jing-yan;HU Peng-wei;CHEN Rui;LU Lei;PEI Xiao-fang;Department of Medical Technology;West China School of Public Health;Sichuan University;Department of Microbiology and Immunology Technology;School of Medical Technology;Chengdu University of Traditional Chinese Medicine;
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Association of Collagen TypeⅠ α1 Sp1 Polymorphism with Intervertebral Disc Degeneration in Han Elderly People
LIN Peng;FU Qiao;Department of Rehabilitation Medicine;the People’s Hospital of Hainan Province;
LIN Peng;FU Qiao;Department of Rehabilitation Medicine;the People’s Hospital of Hainan Province;
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Changes of Bone Mineral Density and Bone Metabolic Marker in Patients with Subclinical Hypothyroidism
LIANG Li-bo;WANG You-juan;ZHANG Mei;HUANG Heng-jian;LI Shuang-qing;Department of General Medicine;West China Hospital;Sichuan University;Department of Physical Examination Center;West China Hospital;Sichuan University;Department of Laboratory Medicine;West China Hospital;Sichuan University;
LIANG Li-bo;WANG You-juan;ZHANG Mei;HUANG Heng-jian;LI Shuang-qing;Department of General Medicine;West China Hospital;Sichuan University;Department of Physical Examination Center;West China Hospital;Sichuan University;Department of Laboratory Medicine;West China Hospital;Sichuan University;
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The Over-expression of STAT1 and IFN-γin Lesions of Human Oral Lichen Planus
HE Juan;CAI Yang;Deptment of Stomatology;the Affiliated Hospital of Guiyang Medical College;Deptment of Stomatology;No.2 Affiliated Hospital of Guiyang College of Traditional Chinese Medicine;
HE Juan;CAI Yang;Deptment of Stomatology;the Affiliated Hospital of Guiyang Medical College;Deptment of Stomatology;No.2 Affiliated Hospital of Guiyang College of Traditional Chinese Medicine;
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Prevalence and Factors Associated with the Prevention and Control of Hypertension in Chinese Yi Populations
GAO Yun;CHEN Tao;RAN Xing-wu;REN Yan;XIE Xiao-hua;TIAN Hao-ming;Department of Endocrinology and Metabolism;West China Hospital;Sichuan University;Department of Endocrinology and Metabolism;the First People’s Hospital of Liangshan Yi Nationality Autonomy District;
GAO Yun;CHEN Tao;RAN Xing-wu;REN Yan;XIE Xiao-hua;TIAN Hao-ming;Department of Endocrinology and Metabolism;West China Hospital;Sichuan University;Department of Endocrinology and Metabolism;the First People’s Hospital of Liangshan Yi Nationality Autonomy District;
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Prevalence of Dibetes and Impaired Glucose Regulation in Chengdu Populations and Associated Dietary Risk Factors
DAI Hua;CHEN Li-yu;LI Shuang-qing;Department of General Medicine;West China Hospital;Sichuan University;Center of Infectious Disease;West China Hospital;Sichuan University;
DAI Hua;CHEN Li-yu;LI Shuang-qing;Department of General Medicine;West China Hospital;Sichuan University;Center of Infectious Disease;West China Hospital;Sichuan University;
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Telemetry EEG of Parietal Association Cortex in Heroin-induced CPP Rats
PAN Qun-wan;ZHU Zai-man;LI Jing;LI Min;ZHOU Hong-min;Department of Physiology;Wannan Medical College;Morphology Experimental Center;Wannan Medical College;
PAN Qun-wan;ZHU Zai-man;LI Jing;LI Min;ZHOU Hong-min;Department of Physiology;Wannan Medical College;Morphology Experimental Center;Wannan Medical College;
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Assessing Heart Function of Patients with Single Left Ventricular Valvalar Insufficiency Leision using 64-slice Multi- detector Row CT Angiography
ZHANG Tai-ming;DONG Li;YUAN Ye;HOU Jiang-long;YANG Zhi-gang;GUO Ying-kun;Deparment of Cardiovascular Surgery;West China Hospital;Sichuan University;Deparment of Cardiac Surgery;Daping Hospital of Third Military Medical University;Deparment of Radiology;West China Hospital;Sichuan University;
ZHANG Tai-ming;DONG Li;YUAN Ye;HOU Jiang-long;YANG Zhi-gang;GUO Ying-kun;Deparment of Cardiovascular Surgery;West China Hospital;Sichuan University;Deparment of Cardiac Surgery;Daping Hospital of Third Military Medical University;Deparment of Radiology;West China Hospital;Sichuan University;
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Risk Stratification of Diabetic Chronic Kidney Disease Using eGFR Equations
ZHOU Jun;ZHANG Mei;SONG Hao-lan;YANG Fu-ju;HUANG Heng-jian;LI Shuang-qing;Department of Laboratory Medicine;West China Hospital;Sichuan University;Department of Laboratory Medicine;Affiliated Hospital of Chengdu University of Traditional Chinese Medicine;Department of General Practice;West China Hospital;Sichuan University;
ZHOU Jun;ZHANG Mei;SONG Hao-lan;YANG Fu-ju;HUANG Heng-jian;LI Shuang-qing;Department of Laboratory Medicine;West China Hospital;Sichuan University;Department of Laboratory Medicine;Affiliated Hospital of Chengdu University of Traditional Chinese Medicine;Department of General Practice;West China Hospital;Sichuan University;
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Breast Cancer Screening of 20 000 Women in Guizhou Province
NI Qing;WEI Na;SU Shi-qiong;JIANG Qing;SUN Qian;QI Jun;JIA Qi;GU Li;Department of Breast Surgery;Guizhou Provincial People’s Hospital;Department of Radiology;Guizhou Provincial People’s Hospital;
NI Qing;WEI Na;SU Shi-qiong;JIANG Qing;SUN Qian;QI Jun;JIA Qi;GU Li;Department of Breast Surgery;Guizhou Provincial People’s Hospital;Department of Radiology;Guizhou Provincial People’s Hospital;
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Arguments and Debates about Physical Therapies for Osteoporosis and Osteoarthritis
HE Cheng-qi;WANG Pu;Center of Rehabilitation Medicine;West China Hospital;Sichuan University;Rehabilitation Key Laboratory of Sichuan Province;
HE Cheng-qi;WANG Pu;Center of Rehabilitation Medicine;West China Hospital;Sichuan University;Rehabilitation Key Laboratory of Sichuan Province;
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Pulsed Electromagnetic Field Therapy Inhibits Chondrocyte Apoptosis in Rabbits with Osteoarthritis
XIE Wei;ZHOU Jun;LUO Qing-lu;LIU Hui-fang;HE Cheng-qi;Center of Rehabilitation Medicine;West China Hospital;Sichuan University;Rehabilitation Key Laboratory of Sichuan Province;Department of Rehabilitation Medicine;the First Affiliated Hospital of Nanhua University;
XIE Wei;ZHOU Jun;LUO Qing-lu;LIU Hui-fang;HE Cheng-qi;Center of Rehabilitation Medicine;West China Hospital;Sichuan University;Rehabilitation Key Laboratory of Sichuan Province;Department of Rehabilitation Medicine;the First Affiliated Hospital of Nanhua University;
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Effects of Whole Body Vibration on Structural and Functional Remodeling of Subchondral Bones in Rabbits with Early Osteoarthritis
WANG Pu;WEI Xiao-fei;YANG Xiao-tian;ZHOU Yu-jing;LIU Chuan;JI Qiao-dan;YANG Lin;HE Cheng-qi;Center of Rehabilitation Medicine;West China Hospital;Sichuan University;Rehabilitation Key Laboratory of Sichuan Province;
WANG Pu;WEI Xiao-fei;YANG Xiao-tian;ZHOU Yu-jing;LIU Chuan;JI Qiao-dan;YANG Lin;HE Cheng-qi;Center of Rehabilitation Medicine;West China Hospital;Sichuan University;Rehabilitation Key Laboratory of Sichuan Province;
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The Effect of Low-frequency Pulsed Electromagnetic Fields on Balance Ability of Patients with Post-menopausal Osteoporosis
HE Hong-chen;XU Jian;YANG Lin;WU Yuan-chao;XIONG En-fu;XIE Wei;HE Cheng-qi;Center of Rehabilitation Medicine;West China Hospital;Sichuan University;Rehabilitation Key Laboratory of Sichuan Province;Department of Osteoporosis;West China Fourth Hospital;Sichuan University;
HE Hong-chen;XU Jian;YANG Lin;WU Yuan-chao;XIONG En-fu;XIE Wei;HE Cheng-qi;Center of Rehabilitation Medicine;West China Hospital;Sichuan University;Rehabilitation Key Laboratory of Sichuan Province;Department of Osteoporosis;West China Fourth Hospital;Sichuan University;
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Effect of Extracorporeal Shock Wave Therapy on Cartilage and Subchondral Bone Remodeling in Rabbits with ACLT- induced Osteoarthritis
WANG Pu;LIU Chuan;YANG Xiao-tian;WEI Xiao-fei;ZHOU Yu-jing;YANG Lin;HE Cheng-qi;Center of Rehabilitation Medicine;West China Hospital;Sichuan University;Rehabilitation Key Laboratory of Sichuan Province;
WANG Pu;LIU Chuan;YANG Xiao-tian;WEI Xiao-fei;ZHOU Yu-jing;YANG Lin;HE Cheng-qi;Center of Rehabilitation Medicine;West China Hospital;Sichuan University;Rehabilitation Key Laboratory of Sichuan Province;
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The Effect of Elastic Taping on Patients with Patellofemoral Syndrome
YANG Lin;JIANG Jun-liang;LIANG Qiu;LEI Zhong-jie;HE Cheng-qi;Center of Rehabilitation Medicine;West China Hospital;Sichuan University;Rehabilitation Key Laboratory of Sichuan Province;
YANG Lin;JIANG Jun-liang;LIANG Qiu;LEI Zhong-jie;HE Cheng-qi;Center of Rehabilitation Medicine;West China Hospital;Sichuan University;Rehabilitation Key Laboratory of Sichuan Province;
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The Therapeutic Effect of Neurac Training on Patients with Cervical Radiculopathy:a Randomized Control Trial
YANG Lin;LEI Zhong-jie;JIANG Jun-liang;ZHANG Li-ming;HE Cheng-qi;Center of Rehabilitation Medicine;West China Hospital;Rehabilitation Key Laboratory of Sichuan Province;
YANG Lin;LEI Zhong-jie;JIANG Jun-liang;ZHANG Li-ming;HE Cheng-qi;Center of Rehabilitation Medicine;West China Hospital;Rehabilitation Key Laboratory of Sichuan Province;
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The Estrogen-like and Antioxidant Effects of Pilose Antler Blood Wine in Female Rats with Ovariectomy
GAO Qiang;YANG Yang;SUN Zeng-chun;JIANG Hua;JIA Xue;YUAN Ju-lian;HE Cheng-qi;Center of Rehabilitation Medicine;West China Hospital;Sichuan University;Institute of Disaster Management and Reconstruction;Sichuan University-The Hong Kong Polytechnic University;Rechabilitation Key Laboratory of Sichuan Province;
GAO Qiang;YANG Yang;SUN Zeng-chun;JIANG Hua;JIA Xue;YUAN Ju-lian;HE Cheng-qi;Center of Rehabilitation Medicine;West China Hospital;Sichuan University;Institute of Disaster Management and Reconstruction;Sichuan University-The Hong Kong Polytechnic University;Rechabilitation Key Laboratory of Sichuan Province;
..............page:134-137
Isolation of Mouse Primary Hepatocytes by Retrograde Liver Perfusion with Catheterization via Heart
YU Zhao-yan;BAI Yan-nan;ZHANG Tao;WU Hong;ZENG Yong;Department of Hepato-Biliary-Pancreatic Surgery;West China Hospital;Sichuan University;
YU Zhao-yan;BAI Yan-nan;ZHANG Tao;WU Hong;ZENG Yong;Department of Hepato-Biliary-Pancreatic Surgery;West China Hospital;Sichuan University;
..............page:138-141
Simultaneous Determination of Adrenaline,Noradrenaline,Cortisone and Cortisol in Plasma with HPLC/MS/MS
YONG Li;WANG Yu;ZOU Xiao-li;ZHU Lan;XIE Hui-xu;LI Long-jiang;Center for Disease Control and Prevention of Sichuan Province;Department of Sanitary Technology;West China School of Public Health;Sichuan University;State Key Laboratory of Oral Disease Research;Sichuan University;
YONG Li;WANG Yu;ZOU Xiao-li;ZHU Lan;XIE Hui-xu;LI Long-jiang;Center for Disease Control and Prevention of Sichuan Province;Department of Sanitary Technology;West China School of Public Health;Sichuan University;State Key Laboratory of Oral Disease Research;Sichuan University;
..............page:142-146
Preparation of Sodium Aescinat Micro-emulsion for Injection
LI Zi-wei;HUANG Hua;QIN Yao;XIAO Kun-quan;LUO Wei-zao;YANG Yong;GU Dan-dan;Department of Pharmaceutics;Chongqing Medical University;Taiji Group;Chongqing Institute of Traditional Chinese Medicine;Key Laboratory of Natural Resources of Chinese Medicinal Materials of Chongqing;Department of Medicinal Chemistry;Chengdu Chinese Medicine University;
LI Zi-wei;HUANG Hua;QIN Yao;XIAO Kun-quan;LUO Wei-zao;YANG Yong;GU Dan-dan;Department of Pharmaceutics;Chongqing Medical University;Taiji Group;Chongqing Institute of Traditional Chinese Medicine;Key Laboratory of Natural Resources of Chinese Medicinal Materials of Chongqing;Department of Medicinal Chemistry;Chengdu Chinese Medicine University;
..............page:147-151
EMA-PCR Detection of Enterohemorrhagic Eschrichia Coli O157∶H7
HUANG Ruo-ying;FANG Mei;LUO Ying-shu;LIU Heng-chuan;LU Qiao-rong;WANG Guo-qing;West China School of Public Health;Sichuan University;Kunshan Center For Disease Control and Prevention;
HUANG Ruo-ying;FANG Mei;LUO Ying-shu;LIU Heng-chuan;LU Qiao-rong;WANG Guo-qing;West China School of Public Health;Sichuan University;Kunshan Center For Disease Control and Prevention;
..............page:152-155
ying yong shu zi ji guang san ban ji shu fen xi bi jiao zhong zhi yu chuan tong dan duan gu ding qiao de shou zai wei yi
zhao xiao rong ; chen xin min ; zeng xing zuo ;
zhao xiao rong ; chen xin min ; zeng xing zuo ;
..............page:156-158
3t ci gong zhen kuo san jia quan cheng xiang dui gong jing ai pen qiang zhuan yi lin ba jie de zhen duan jia zhi
liu ling ; pan yun ; ning gang ; guo ying kun ; li chang xian ; ou yang qin ;
liu ling ; pan yun ; ning gang ; guo ying kun ; li chang xian ; ou yang qin ;
..............page:159-163
man xing huo dong xing eb bing du gan ran jin zhan wei da b xi bao lin ba liu 1 li bao gao
lu jia zuo ; xu huan ; tang hong ;
lu jia zuo ; xu huan ; tang hong ;
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di zhen hou ban fang she qu lao nian ren gu du gan ji ying xiang yin su diao cha yan jiu
chen zuo ling ; chen hong ; li zuo ; qu mei lan ; feng ling ; guo hong xia ; chen zuo ; qian huang bi jun ;
chen zuo ling ; chen hong ; li zuo ; qu mei lan ; feng ling ; guo hong xia ; chen zuo ; qian huang bi jun ;
..............page:164-166
The Clinical Significance of Preoperative Enteral Immune Nutrition in Patients with Malignant Gastrointestinal Tumors
HUANG Zheng-jie;CHEN Bai-sheng;YOU Jun;WU Bing-lin;JIANG Long;FENG Qing-zhao;LUO Qi;Department of Surgical Oncology;the First Affiliated Hospital of Xiamen University;The First Clinical Medical College;Fujian Medical University;
HUANG Zheng-jie;CHEN Bai-sheng;YOU Jun;WU Bing-lin;JIANG Long;FENG Qing-zhao;LUO Qi;Department of Surgical Oncology;the First Affiliated Hospital of Xiamen University;The First Clinical Medical College;Fujian Medical University;
..............page:167-170
bing fa xiong xian liu de fu zhong liu xing tian zuo chuang 1 li bao gao
yi qin ; chen zuo ; jiang xian ; xia deng mei ; guo zai pei ;
yi qin ; chen zuo ; jiang xian ; xia deng mei ; guo zai pei ;
..............page:170
msctu zai er tong shu niao guan yi wei kai kou ding wei zhen duan zhong de ying yong
wang qiu xia ; hu dao yu ; chen liang ;
wang qiu xia ; hu dao yu ; chen liang ;
..............page:171-173
ji wang shen zang shou shu shi dui tong ce shen jie shi xing pcnl de ying xiang
xu peng ; wang zuo ; li yu tao ; shen peng fei ; wei wu ran ; wang jia ;
xu peng ; wang zuo ; li yu tao ; shen peng fei ; wei wu ran ; wang jia ;
..............page:174-176
lou dou xiong huan zhe nuss shou shu qian hou fei gong neng de dui bi fen xi
han bing ; kou zuo ;
han bing ; kou zuo ;
..............page:177-178